Detection and quantitation of tetanus antitoxin in blood donations.

بررسی وضعیت ایمنی علیه کزاز در افراد بالای 50 سال در کاشان

Ojectives: Tetanus is a neurologic disorder which occurs as sporadic cases in people with incomplete vaccination course.The most tetanus patients are people over 60 years of age.It is a important disease in elderly patients because of risk of severe forms and high rate of morbidity and mortality This study was conducted to evaluate tetanus immunity in 50 years of age and older people in kashan-...

Evolution in the Production and control of Equine Tetanus Antitoxin During the last 3 decades in Iran.

Quantitation of commercial equine tetanus antitoxin by competitive enzyme-linked immunosorbent assay.

In the USA, the potency of commercially prepared equine tetanus antitoxin is determined by the method outlined in the Code of Federal Regulations, Title 9, Part 113.451. In the current test, commercial equine tetanus antitoxin is tested by a toxin neutralization test in guinea pigs. The in vivo test measures antitoxin content through effectiveness of protection of guinea pigs injected with dilu...

Diphtheria and tetanus immunity among blood donors in Toronto.

OBJECTIVE To determine the diphtheria and tetanus antitoxin levels among blood donors in Toronto. DESIGN Cross-sectional seroprevalence study. SETTING Two fixed-site blood-donation clinics in Toronto from September to November 1994. PARTICIPANTS Blood donors 20 years of age or older were eligible to participate; of the 781 eligible donors, 710 (90.9%) participated in the study. MAIN OUT...

The Relationship of Toxin and Antitoxin Injection Site to Tetanus Development in the Rat

The pattern of development of symptoms was studied following injection of 3 MLD (minimum lethal dose) of tetanus toxin in each of the following sites in the rat: vein, muscle, endoneurium, epineurium, spinal cord, subarachnoid space, and subdural space. Similar observations were made when 3 MPD (minimum protective dose) of antitoxin were injected into each of the above sites a few minutes after...